Cartia XT® (Diltiazem HCl Extended-Release Capsules, USP)
Moderate Monitor blood pressure and heart rate if coadministration of diltiazem with rucaparib is necessary. High Blood Pressure Hypertension. Side effects in more detail. Monitor blood pressure if the combination is necessary. Acetaminophen; Dextromethorphan; Pseudoephedrine: Moderate Prolongation of the effects of neuromuscular blockers is possible when they are given in combination with calcium-channel blockers, particularly diltiazem. Patients should be monitored for cartia and toxicity. Moderate Ginkgo biloba appears to inhibit the metabolism of calcium-channel blockers, perhaps by inhibiting the CYP3A4 isoenzyme. Studies have shown that drugs that inhibit CYP3A4 can increase avanafil exposure. Diltiazem 90 mg-MYL, white, oblong, film coated. Initially, mg PO once daily, given either in the morning or evening. Side effects in more detail. Ibuprofen; Pseudoephedrine: Both decreased lithium concentrations and lithium toxicity have been reported after the addition of verapamil. If the inhibitor is discontinued after dose adjustments are made, monitor for lack of clozapine effectiveness and consider increasing the clozapine dose if necessary. Moderate Concomitant use of hydrocodone with diltiazem may increase hydrocodone plasma concentrations and prolong opioid adverse reactions, including hypotension, respiratory depression, profound sedation, coma, and death. If you have questions about side effects, call your doctor. Moderate The pharmacologic effects of isoproterenol may cause an increase in blood pressure. Cardizem CD mg, blue, , cartia xt. Lumacaftor; ivacaftor may reduce the efficacy of diltiazem by decreasing its systemic exposure. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:. When an alternative therapy is not possible, patients should be monitored for the desired cardiovascular effects on heart rate, chest pain, or blood pressure. Moderate Consider cartia dose reduction of cannabidiol if coadministered with diltiazem. Medically reviewed on Feb 6, Ibuprofen; Oxycodone:
Learn how to get this Teva generic Teva's generic medications are available in most pharmacies across the United States, though not all pharmacies carry the same Teva medications. Individuals receiving these medications together are at increased risk of developing heart failure. It is theoretically possible that cartia doses of ginger could affect caetia action of inotropes; however, no clinical data are available. Use of diltiazem carria treatment of atrial fibrillation or flutter may cargia severe ventricular arrhythmias and is contraindicated in patients with Wolff-Parkinson-White syndrome or Lown-Ganong-Levine syndrome. Moderate The combination of carti and a beta-blocker, like penbutolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Major Avoid coadministration of diltiazem and doxorubicin if possible. Some patients may respond to an initial bolus dose of 0. Diltiazem is a moderate CYP3A4 inhibitor. Hawthorn, Crataegus laevigata: Moderate The incidence of marijuana caryia adverse effects may change following coadministration with diltiazem. These agents may include diltiazem. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, cartia xt, or adverse effects. Major Decrease deflazacort dose to one third of the recommended dosage when coadministered with diltiazem. Major If diltiazem and ivacaftor are taken together, administer ivacaftor at the usual recommended dose but reduce the frequency to once daily. Cartia Avoid concomitant use of diltiazem with neratinib due to an increased risk of neratinib-related toxicity.
Concomitant use warrants caution due to the potential for increased side effects. A normal heart rate or heart beat is 60 to beats per minute. Buprenorphine; Naloxone: All drugs may cause side effects. Melatonin appeared to antagonize the antihypertensive effects of nifedipine. Explore Apps. Major Coadministration of diltiazem and moricizine may increase both moricizine and diltiazem plasma concentrations. If concurrent treatment with diltiazem is necessary, strongly consider a lapatinib dose reduction. Close monitoring of blood pressure or the selection of alternative therapeutic agents may be needed. If concurrent use of halofantrine and a CYP3A4 inhibitor is warranted, it would be prudent to use caution and monitor the ECG periodically. Severe Concurrent use of pimozide and diltiazem should cartia avoided. The first dose response acute postural hypotension of prazosin may be exaggerated in patients who are receiving beta-adrenergic blockers, cartia xt, diuretics, or other antihypertensive agents. The AAP also considers verapamil, another calcium-channel blocker, to be usually compatible with breast-feeding. There are many drug interactions that can potentiate the effects of antihypertensives. Moderate Monitor blood pressure and heart rate if coadministration of diltiazem with cobicistat is necessary. Major Due to the risk for serious colchicine toxicity including multi-organ failure and death, avoid coadministration of colchicine and diltiazem in patients with normal renal and hepatic function unless the use of both agents is imperative. Use these drugs together cautiously, and monitor the patient for benzodiazepine-related side effects. Cartia patients cartia are also receiving treatment with cyclosporine, the magnitude of this interaction may be amplified. The mechanism of this interaction is unclear. Subscribe to receive email notifications whenever new articles are published. Moderate Monitor for an increase in maraviroc adverse effects with concomitant use of diltiazem due to a possible increase in maraviroc exposure. Administered once-daily morning or evening ; may be administered without regard to meals. Diclofenac; Misoprostol:
Angina Pectoris Prophylaxis aspirinmetoprololdiltiazematenololnitroglycerinnifedipinecartia mononitrateMore And it always seems that my pulse rate is low when I take my pressure with the machine. As a single mg or 40 mg oral dose, the inhibitory effect of aprepitant on CYP3A4 is weak, with the AUC of midazolam increased by 1, cartia xt. My feet have been swelling. Alcohol increases the rate at which some controlled and extended release formulas of diltiazem such as Cardizem CD release diltiazem in vitro. The recommended administration of diltiazem ER may vary depending on the individual product being used. Severe Concurrent use of pimozide and diltiazem should be avoided. Diltiazem mg-MYL, white, oblong, film coated. Moderate Cimetidine can increase the plasma levels of diltiazem, possibly via inhibition of cytochrome P metabolism. Diltiazem is a CYP3A4 substrate. Phentermine; Topiramate: Calcium channel blocking agents Group IV antiarrhythmics. The brand formulation is no longer marketed in the US; however, generics are available. In addition, amiodarone is both a substrate and inhibitor of CYP3A4 metabolism, and may potentially interact with diltiazem via CYP3A4 metabolic cartia. We comply with the HONcode standard for trustworthy health information - cartia here. After the first fingolimod dose, overnight monitoring with continuous ECG in a medical facility is advised for patients who cannot stop taking drugs that slow the heart rate or atrioventricular conduction. Dosage may be increased up to mg per day, given in 3 to 4 divided doses. If diltiazem is discontinued, consider increasing the oxycodone dose until stable drug effects are achieved and monitor for evidence of opioid withdrawal. In one placebo-controlled study, melatonin evening ingestion led to significant increases in blood pressure 6. I take Diltiazem ER mg capsule, twice a day. Systemic drug interactions with the urethral suppository MUSE or alprostadil intracavernous injection are unlikely in most patients because low or undetectable amounts of the drug are found in the peripheral venous circulation following administration.
Worsened psychosis has been reported with the combination of diltiazem and lithium. Moderate Use apixaban and x together with caution in patients with significant renal dysfunction as risk of bleeding may be increased. These agents may include diltiazem. Moderate Be alert for symptoms of ergot toxicity if using ergotamine and diltiazem together is medically necessary. Initially, 30 to 60 mg PO 4 times per day. Mefenamic Acid: These patients may require additional monitoring and information. Fluoxetine; Olanzapine: Moderate Concomitant use of codeine with diltiazem may increase codeine plasma concentrations, resulting in greater metabolism by CYP2D6, increased morphine concentrations, and prolonged opioid adverse reactions, including hypotension, respiratory depression, profound sedation, coma, and death. Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Alfentanil is a sensitive CYP3A4 substrate, and coadministration with CYP3A4 inhibitors cartia diltiazem can increase alfentanil exposure resulting in increased or prolonged opioid effects including fatal respiratory depression, particularly when an inhibitor is added to a stable dose of alfentanil. Significant decreases in diltiazem concentrations could be seen, and significant increases in rifabutin concentrations could be seen. Moderate The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by calcium-channel blockers. If use together is necessary, obtain an ECG prior to lacosamide initiation and after treatment has been titrated to steady-state. Chlorpheniramine; Hydrocodone: As diltiazem is both a substrate and an inhibitor of CYP3A4, monitor patients for corticosteroid-related side effects if prednisone and diltiazem carrtia taken. Diltiazem should be used with extreme caution in patients taking beta-adrenergic cartia agents. Moderate Orthostatic hypotension and syncope have been reported during duloxetine administration. Brompheniramine; Hydrocodone; Pseudoephedrine: Neuromuscular blockers: Although concomitant use of moderate CYP3A4 inhibitors with lomitapide has not been studied, a significant cartia in lomitapide exposure is likely during concurrent use. In addition, itraconazole may increase diltiazem serum concentrations via inhibition of CYP3A4 cargia the potential for diltiazem toxicity, cartia xt. Moderate Use lacosamide with caution in patients taking concomitant medications that affect cardiac conduction, such as calcium-channel blockers, because of the risk of AV block, bradycardia, or ventricular tachyarrhythmia. Carhia Consider a reduced dose of oxycodone with frequent monitoring for respiratory depression and sedation if concurrent use of diltiazem is necessary.
This catia is most significant in patients receiving concurrent antihypertensive agents and long-term NSAID therapy. Discontinue abemaciclib for patients unable to tolerate 50 mg twice daily. Moderate Concomitant cartua of bradycardia-inducing drugs e. Concurrent cimetidine and diltiazem therapy may require a reduction in diltiazem dosage in some patients; monitor cartia response. Moderate Current data suggest that grapefruit juice has a limited cartix on diltiazem bioavailability. Drospirenone; Ethinyl Estradiol: Major Avoid coadministration of olaparib with diltiazem and consider alternative agents with less Caryia inhibition due to increased olaparib exposure. Patients who choose to take hawthorn should receive periodic blood pressure and heart rate monitoring. Close monitoring of blood pressure is recommended until the full effects of the combination therapy are known. Minor Preclinical data suggest that x blockers could decrease the efficacy cartiw photosensitizing agents used in photodynamic therapy. This is not a list of all drugs or health problems that interact with Cartia XT diltiazem long-acting capsules. Because of these potential risks, red yeast rice is best avoided by patients taking diltiazem. Stroke work index improved and exercise endurance deteriorated less in diltiazem-treated patients. Blood pressure should be monitored carefully in all patients receiving diltiazem. The dosage range studied in clinical trials was to mg. This represents a pharmacodynamic, and not a pharmacokinetic, interaction. A variety of skin rashes and pustules have been reported in patients taking Cardizem diltiazem. Cartia information on this page has been compiled xtt use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Could that be from the diltiazem I take? The effectiveness of antihypertensive agents may be diminished during concurrent use of milnacipran, cartia xt. Severe Caution should be taken when cisapride CYP3A4 substrate is prescribed with diltiazem CYP3A4 inhibitor ; the manufacturer of cisapride considers concurrent use cartia. Patients who rely upon renal prostaglandins to maintain renal perfusion may have acute renal blood flow reduction with NSAID usage.Diltiazem
Carbinoxamine; Pseudoephedrine: Cartia of daily oral aprepitant mg, or 1. Print this page Add to My Med List. Some drugs have no effect on weight, while others cause weight gain or weight loss. Diltiazem is an inhibitor of CYP3A4, an isoenzyme cartla responsible for the metabolism of marijuana's most psychoactive compound, deltatetrahydrocannabinol DeltaTHC. Subsequent dosage adjustments should be based on clinical cadtia. Bosentan has been shown to have no pharmacokinetic interactions with nimodipine. Patients should be advised to inform their prescriber of their use of CoQ Minor As diltiazem cartiz CYP3A4 activity, serum estrogen concentrations and estrogenic-related side effects e. Regarding diltiazem, although neurotoxicity was reported after the addition of diltiazem, other drugs were administered concomitantly. Monitor patients for ibrutinib toxicity e. Aldesleukin, IL Continuous IV Infusion Dilute appropriate dose of injection solution in 0, cartia xt. You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. The manufacturer advises that Cartia diazoxide should not be administered to patients within 6 hours of fartia other antihypertensive agents. However, many people have no side effects or only have minor side effects.
Moderate Fluoxetine may decrease the clearance of calcium-channel blockers via inhibition of CYP3A4 metabolism. Ethinyl Estradiol; Levonorgestrel: Generalized body aches are not listed as a side effect of diltiazem in the package insert. Amlodipine; Telmisartan: Use caution when administering these drugs concomitantly. Transfer contents to a graduated cylinder and adjust to a final volume of mL, cartia xt. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Drospirenone; Estradiol: Drospirenone; Ethinyl Estradiol: You may also report side effects at http: Moderate Additive hypotensive effects may be seen when monoamine oxidase inhibitors MAOIs are combined with antihypertensives. Because cartia the significant impact on neratinib exposure from strong CYP3A4 inhibition, the potential impact on neratinib safety from concomitant use with moderate CYP3A4 inhibitors should be considered as cartia may also significantly increase neratinib exposure. Moderate Monitor blood pressure and heart rate if coadministration of diltiazem with palbociclib is necessary. This is not a common side effect of diltiazem Cardizem. Call your doctor for medical advice about side effects. Aprepitant, Fosaprepitant: Nonsteroidal antiinflammatory drugs: Coadministration may increase the exposure of both drugs.
Uses of Cartia XT:
Diltiazem is metabolized by CYP3A4. Diltiazem direct compression catia For additional information regarding diltiazem: Moderate Diltiazem has been reported to increase the plasma level and hypotensive effects of nifedipine via CYP3A4 inhibition. Major Concomitant use of bretylium with other antiarrhythmis, such as diltiazem, cartiaa have additive, antagonistic, cartia xt, or synergistic electrophysiologic, pharmacodynamic, or toxic effects, including hypotension. Individual patients may respond to higher doses up to mg per day. Available for Android and iOS devices. You ct check to make cartia that it is safe for you to take Cartia XT diltiazem long-acting capsules with all of your drugs and health problems. Stroke work index improved and exercise cartia deteriorated less in diltiazem-treated patients. Call your doctor or get medical help if any of these side effects cartja any other side effects bother you or do not go away:. Cartia XT mg, orange, capsule. Patients should be monitored more closely for hypotension if nitroglycerin, including nitroglycerin rectal ointment, is used concurrently with a calcium-channel blocker. Moderate Concomitant administration of bradycardia-inducing drugs e. Call your doctor for medical advice about side effects. Conjugated Estrogens; Bazedoxifene: If diltiazem is discontinued, consider increasing the fentanyl dose until stable drug effects are achieved and monitor for evidence of opioid withdrawal.
Moderate The combination of diltiazem and a beta-blocker, like acebutolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Alternatively, cherry syrup may be substituted for base solution mixture. Diltiazem mg-TEV, orange, oval,. Do not use the IV formulation in patients with wide-complex ventricular tachycardia as these patients are at risk of developing ventricular fibrillation after intravenous diltiazem. Patients being given lofexidine in an outpatient setting should be capable of and instructed on self-monitoring for hypotension, orthostasis, bradycardia, and associated symptoms. Dextromethorphan; Guaifenesin; Phenylephrine: All drugs may cause side effects. Drospirenone; Estradiol: Moderate Concomitant use of clindamycin and diltiazem may decrease clindamycin clearance and increase the risk of adverse reactions. Medically reviewed on Feb 11, Major Diltiazem has been shown to increase encainide AUC and half-life. Cardizem CD mg, turquoise, capsule,. Moderate Indinavir may inhibit the metabolism of other medications that are metabolized via cytochrome P 3A4. Coadministration of eliglustat with CYP3A inhibitors, such as diltiazem, may increase eliglustat exposure and the risk of serious adverse events e. Patients taking antihypertensive agents may need to have their therapy modified. Monitor patients receiving these drugs concurrently for altered clinical response to therapy. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:.
Uses of Cartia XT:
Major Patients must avoid consumption of alcohol with some dosage forms of diltiazem; also, advise patients to limit alcohol ingestion with diltiazem in general since there may be additive effects on blood pressure that may increase the risk for orthostatic hypotension, dizziness or syncope. Also, the same medications can cause weight gain in certain individuals and weight loss in others. Exercise caution when co-administering systemic azole antifungals and calcium-channel blockers. Grapefruit juice: Caution is recommended when administering these medications in combination. Homatropine; Hydrocodone: In some studies, skeletal abnormalities have been reported. Acetaminophen; Dextromethorphan; Pseudoephedrine: Moderate The combination of diltiazem and a beta-blocker, like nebivolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Brompheniramine; Pseudoephedrine: Drug Status Rx. Carbinoxamine; Hydrocodone; Phenylephrine: It's possible that edema, or swelling, may occur from taking diltiazem. Where can I find Teva medications? Also, getting into the habit of taking a medication at the same time each day provides a regular routine, which can help prevent missed doses. Maximum antihypertensive effect is usually observed by 14 days of chronic therapy; therefore, schedule dosage adjustments accordingly. In a double-blind, multicenter study, patients with idiopathic dilated cardiomyopathy were randomized to either diltiazem or placebo. Although drug interaction studies have not been conducted, the serum concentration of diltiazem may be increased with concomitant administration of saquinavir. The usual dosage range during clinical studies was to mg PO twice daily. Moderate Concomitant administration of bradycardia-inducing drugs e. In patients with hypertension receiving a concurrent CYP3A4 inhibitor, initiate eplerenone at 25 mg PO once daily; the dose may be increased to a maximum of 25 mg PO twice daily for inadequate blood pressure response.
Vials are unpreserved, single-use containers. Change to every other day dosing if the reduced dose is lower than the lowest available strength. Where can I find Teva medications? It is possible that additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. When an alternative therapy is not possible, patients should be monitored for the desired cardiovascular effects on heart rate, chest pain, or blood pressure, as well as associated rifabutin side effects. Tiazac mg, blue, capsule,. Do not store for later use. If the pharmacy doesn't regularly stock a certain medication from Teva, ask if it can be ordered for you at no additional cost. Amlodipine; Telmisartan: Should this be taken with or without food or on an empty stomach? They are the same drug, but they are not interchangeable. If these drugs are given together, closely monitor for diltiazem-related adverse events e. Lumacaftor is a strong CYP3A inducer. Although clinical studies have not been done to determine the clinical significance of such an interaction, the potential for increased adverse effects and toxicity associated with elevated plasma levels of escitalopram theoretically exists. Careful blood pressure monitoring is recommended. Some drugs have no effect on weight, while others cause weight gain or weight loss. Bendroflumethiazide; Cartia Skip to Content. Do not stop any medication or change the dose without first talking to your provider. Angina Pectoris Prophylaxis aspirincartia xt, metoprolol catia, diltiazematenololnitroglycerinnifedipineisosorbide mononitrateMore Read all information given to you. Co-Enzyme Q10, Ubiquinone: Diltiazem should be used with extreme caution in patients taking beta-adrenergic blocking agents. Moderate Fluconazole may decrease the clearance of calcium-channel blockers, including diltiazem, via inhibition of CYP3A4 metabolism.
Brompheniramine; Carbetapentane; Phenylephrine: Nonsteroidal antiinflammatory drugs: Animal studies involving doses ranging from 5 to 10 times greater than the daily recommended therapeutic dose has resulted in embryo and fetal death. In addition, diltiazem inhibits CYP3A4, a partial pathway for propafenone metabolism. Consider a cariprazine dose reduction if hypotension occurs. Moderate Consider a reduced dose of oxycodone with frequent monitoring for respiratory depression and sedation if concurrent use of diltiazem is necessary. After 24 months, survival was similar in the diltiazem and placebo groups. Moderate The combination of diltiazem and a beta-blocker, like nadolol, is usually well tolerated; the combination is often used for their combined therapeutic benefits to reduce angina and improve exercise tolerance. Major If coadministered with dronedarone, initiate diltiazem at a low dose and increase only after ECG verification of good tolerability. Also, the same medications can cause weight gain in certain individuals and weight loss in others. Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. In addition, amiodarone is both a substrate and inhibitor of CYP3A4 metabolism, and may potentially interact with diltiazem via CYP3A4 metabolic pathways. Diltiazem Cardizem is a calcium channel blocker used to treat hypertension high blood pressure , angina chest pain , and some forms of irregular heart rhythms. Moderate The concomitant administration of tamsulosin with other antihypertensive agents can cause additive hypotensive effects. Cardizem LA mg, white, oblong,. Systemic drug interactions with the urethral suppository MUSE or alprostadil intracavernous injection are unlikely in most patients because low or undetectable amounts of the drug are found in the peripheral venous circulation following administration. Melatonin appeared to antagonize the antihypertensive cartia of nifedipine. Closely monitor patients for ixabepilone-related toxicities. Learn how to get this Teva generic Teva's generic medications are available in most pharmacies across the United States, though not all pharmacies carry the same Teva medications. Moderate Fluvoxamine may decrease the clearance of calcium-channel blockers, including diltiazem, via inhibition of CYP3A4 metabolism. Amitriptyline; Chlordiazepoxide: In theory, the CYP3A4 inhibitory effects of diltiazem may result in an increase in plasma concentrations of 5-hydroxymethyltolterodine. It should be taken with a full glass of water, either with or without food, cartia xt. Belladonna Alkaloids; Ergotamine; Phenobarbital: Diltiazem should be used with extreme caution in patients taking beta-adrenergic blocking agents.